ToungeInCheek since 2010
10 Year Member
If I understand it correctly, IgM is the initial antibody response post-infection, and is short lived, and IgG is the "memory" antibody that would enable the host to fight off subsequent infections, right?
So when researchers are looking at subsequent immunity, they would be looking for the IgG antibody? Would there be a difference in IgG levels based on the severity of symptoms?
That is correct. It is the process of class switching that allows the immunoglobulins end up IgG1 IgG2 IgA, IgD etc. IgM lacks the specificity. I get out of my element fairly quickly when talking immunology.